Thursday, April 25, 2013

Four children die in S. Carolina mobile home fire

HARTSVILLE, S.C. (AP) ? Authorities say four children have been killed in a mobile home fire in the South Carolina city of Hartsville.

Darlington County Coroner Todd Hardee said twin 1-year-old girls and their brothers aged 3 and 4 were found dead in the home after the fire was put out Wednesday afternoon.

Hardee said autopsies have been scheduled for Thursday to determine the cause of death and their identities.

Sheriff Wayne Byrd said the mother was in the yard when firefighters arrived. He didn't elaborate.

The fire is under investigation by both the sheriff 's department and the State Law Enforcement Division. No charges have been filed and authorities were preparing to talk with the mother.

Hartsville is a city of some 8,000 people about 60 miles east of the state capital, Columbia.

Source: http://news.yahoo.com/official-4-children-killed-sc-mobile-home-fire-195420381.html

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Repairing articular cartilage defects with an injectable gel engineered with gene modified BMSCs

Apr. 23, 2013 ? Researchers at Micro Orthopaedics, Zhongnan Hospital of Wuhan University, led by Dr. Ai-xi Yu, have suggested that articular cartilage defects can be repaired by a novel thermo-sensitive injectable hydrogel engineered with gene modified bone marrow mesenchymal stromal cells (BMSCs). The chitosan and polyvinyl alcohol composite hydrogel containing hTGF?-1 gene modified BMSCs was injected into rabbits with defective articular cartilage. Sixteen weeks later the defected cartilage regenerated and was proven to be hyaline cartilage.

This work can be found in the January 2013 issue of Experimental Biology and Medicine.

"No reliable approach is currently available for complete restoration of damaged articular cartilage," said Dr. Bai-wen Qi, "in this study, CS/PVA gel was combined with rabbit bone marrow stromal cells (BMSCs) transfected with hTGF?-1 and used to repair rabbit articular cartilage defects and the repair effect was evaluated."

Tissue engineering combined with gene therapy technology has the potential to manage the repair of defective articular cartilage. In this study, through minimally invasive injection methods the authors were able to repair rabbit articular cartilage defects with CS/PVA gel and gene modified BMSCs. Dr. Qi said "CS/PVA gel can be applied to the repair of articular cartilage defects as an injectable material in tissue engineering, and the regenerated cartilage can secrete cartilage matrix and perform the functions of hyaline cartilage. Use of this gel for cartilage repair has advantages such as the minor surgical procedure required, tight bonding with the damaged tissue and lack of rejection."

Dr. Steven R. Goodman, Editor-in-Chief of Experimental Biology and Medicine said "The study by Qi and colleagues is very exciting as it combines tissue engineering and gene therapy approaches to successfully repair defective articular cartilage. The approach should be adaptable in the future to human tissue repair."

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The above story is reprinted from materials provided by Society for Experimental Biology and Medicine, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. B.-w. Qi, A.-x. Yu, S.-b. Zhu, M. Zhou, G. Wu. Chitosan/poly(vinyl alcohol) hydrogel combined with Ad-hTGF-?1 transfected mesenchymal stem cells to repair rabbit articular cartilage defects. Experimental Biology and Medicine, 2013; 238 (1): 23 DOI: 10.1258/ebm.2012.012223

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/ECzWDwvlCpc/130423144307.htm

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NASCAR penalizes Kenseth after engine fails

Sprint Cup Series driver Matt Kenseth (20) leads the field as the green flag drops to start a NASCAR Sprint Cup series race at Kansas Speedway in Kansas City, Kan., Sunday, April 21, 2013. (AP Photo/Orlin Wagner)

Sprint Cup Series driver Matt Kenseth (20) leads the field as the green flag drops to start a NASCAR Sprint Cup series race at Kansas Speedway in Kansas City, Kan., Sunday, April 21, 2013. (AP Photo/Orlin Wagner)

Matt Kenseth (20) celebrates in Victory Lane after winning the NASCAR Sprint Cup Series auto race at Kansas Speedway in Kansas City, Kan., Sunday, April 21, 2013. (AP Photo/Orlin Wagner)

CHARLOTTE, N.C. (AP) ? NASCAR has a zero tolerance policy when it comes to engines, tires and fuel on a race car. Anything even slightly improper is dealt with swiftly and severely. NASCAR always throws the book at offenders.

Matt Kenseth and Joe Gibbs Racing were no exception, getting hit with one of the largest penalties in NASCAR history Wednesday after the engine from Kenseth's race-winning car at Kansas failed a post-race inspection. The team had nothing to do with the error, and manufacturer Toyota immediately accepted responsibility for one of eight connecting rods failing to meet the minimum weight requirement by 3 grams ? less than an empty envelope.

"We take full responsibility for this issue with the engine. JGR is not involved in the process of selecting parts or assembling the Cup Series engines," Toyota Racing Development President Lee White said.

It's been a busy season for NASCAR discipline. In February, Nationwide Series driver Jeremy Clements was suspended after an apparently insensitive remark to an MTV blogger and Denny Hamlin was fined $25,000 for criticizing the new Gen-6 race car.

But in the past week, NASCAR has levied more than $450,000 in fines, suspended nearly a dozen crew members for upcoming points races, and knocked some of the top drivers in its series out of the top five as it punishes teams for rules violations involving the cars themselves.

Kenseth was stripped of everything but the trophy from Sunday's win at Kansas.

He was docked 50 driver points in the standings ? he earned only 48 points for the victory ? and NASCAR also erased the three bonus points he earned for the win that would have been applied in seeding for the Chase for the Sprint Cup championship. In addition, the victory will not be credited toward his eligibility for a wild card berth in the Chase.

So, although Kenseth has two wins on the year, the Kansas win does not count in any form toward Chase eligibility. He lost his pole award, too, which could hurt eligibility for next year's Sprint Unlimited exhibition race.

The penalty to Kenseth, who held off Kasey Kahne of Hendrick Motorsports to earn his second win of the season, dropped him from eighth to 14th in the standings.

NASCAR also suspended crew chief Jason Ratcliff for six races and fined him $200,000. And in a rare move, car owner Joe Gibbs had his owner's license suspended for the next six races and he won't earn car owner points during that time. He also was docked 50 car owner points while Toyota, which supplies the JGR engines through Costa Mesa, Calif.-based TRD, lost five points in the manufacturer standings.

JGR said it would appeal.

"It is our understanding that one of the eight connecting rods on the engine was ruled too light," the statement said. "We are working with our partners at TRD on this issue."

White said Kenseth gained no advantage from the light rod.

"It was a simple oversight on TRD's part and there was no intent to deceive, or to gain any type of competitive advantage," White said. "Toyota is a company that was built on integrity, and that remains one of the guiding principles of the company. The goal of TRD has always been ? and will continue to be ? to build high-performance engines that are reliable, durable and powerful, and within the guidelines established by NASCAR."

It's the second severe penalty against a Sprint Cup team levied by NASCAR in as many weeks.

It was Penske Racing and defending Sprint Cup champion Brad Keselowski who were punished last week after NASCAR said it found unapproved parts in the rear suspension of Keselowski and Joey Logano's cars at Texas. NASCAR docked 25 points each the drivers, fined the crew chiefs $100,000 each and suspended seven Penske employees for six races. Penske Racing's appeal is scheduled for May 1.

Those penalties were for alterations to the body of the car, particularly in an area NASCAR has been working the last year to police after teams found a way to manipulate the skew of the cars last season. Team owner Roger Penske has maintained the team was not cheating, but "working in a gray area" of the rule book.

It's not clear if that argument will fly before the three-member appeal board, and the 2013 rule book was specifically tightened this season to add language specific to the rear suspension systems.

In the case of JGR and the engine, illegal is illegal and there is no gray area.

NASCAR has proven that through penalties before. The last violator, Carl Long, was severely punished when he was found to have an illegal engine at the 2009 All-Star Race. Long was docked 200 points ? which would be about 50 points under the current points system ? fined $200,000 and suspended for 12 races.

His suspension was reduced to eight races on appeal, but Long has said he is unable to pay the fine and can't work in Sprint Cup until he settles the debt.

"We've always known the engine and tires are sacred ground. You don't mess with the engine or the tires," said former crew chief and current Fox analyst Larry McReynolds, who added that all eight connecting rods would have been light if TRD was trying to cheat.

"This was pure human error," McReynolds said. "But in NASCAR's defense, they can't completely determine intent or non-intent. They absolutely should appeal. I'd primarily appeal Ratcliff's suspension. He was an innocent bystander in this. The engine is a different deal than the rest of the car. If I was Joe Gibbs, I'd be pretty ticked off about losing my crew chief under these circumstances. This was an error but an enormously costly one."

JGR has the means to pay the fine and the personnel to recover from this setback. The appeal would likely be to reduce the penalties on the argument it was TRD that erred and the team had no control or access to assembly of the engine.

Kenseth is unlikely to get back his bonus points. NASCAR stripped Carl Edwards of his 10 bonus points under an older scoring system for not having a cover on his oil tank after a 2008 win at Las Vegas. The victory stood, but Edwards was not able to carry the 10 bonus points into the Chase. His crew chief was also suspended six races.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-04-24-CAR-NASCAR-Kenseth-Engine-Issue/id-88b4691b3781457491ee46439b291ad6

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Wednesday, April 24, 2013

Warm weather helps drive surge in motorcycle deaths

Alan Spearman / The Commercial Appeal file

Driver Jimmy Vinson waits for the scene of a motorcycle accident to be cleared on March 26, 2012, in Memphis, Tenn. No one died in this crash, but more than 5,000 riders were killed nationwide last year, according to preliminary accident data.

By Mark Schone, NBC News

U.S. motorcyclist deaths surged 9 percent last year to more than 5,000 -- near a record high -- in part because warm weather lured more riders out on the road last spring, but also because of a long-term decline in helmet laws, according to a report issued Wednesday by the Governors Highway Safety Association.

"All of the trends with motorcycle deaths are really going in the wrong direction," said GHSA Chairman Kendell Poole, highway safety director for the state of Tennessee. "We are talking about 5,000 tragedies a year with no sign of progress."

The projected rise, based on preliminary accident data, outpaced the national increase in overall traffic fatalities, which rose from 5 percent to 7 percent in 2012, and marked the 14th time in the past 15 years that motorcycle deaths have increased. Over the same period, traffic deaths involving all varieties of vehicles have fallen by 23 percent, according to the GHSA.

"The most notable thing was the warm weather," said Dr. James Hedlund, the author of the report and a former official with the National Highway Traffic Safety Administration. "Motorcyclists in a number of Northern states were out on the road a lot earlier." Thirty-four states east of the Rocky Mountains notched record average temperatures from March to May 2012.

Read the GHSA report: Motorcyclist Traffic?Fatalities by State

The report also cited two economic factors that may have contributed to an increase in the number of miles traveled via motorcycle in 2012 and a higher probability of accidents: a better economy and high gas prices.

"An improving economy and produces more discretionary income with which to buy and ride motorcycles," said the study. Several states reported an increase in the number of registrations in 2012, likely because of improved economic conditions. Hedlund has found that over the past three decades, the number of registrations tracks closely with the number of deaths.

The improving economy may also have contributed to the increase in overall motorist fatalities in 2012, since more disposable income means more miles driven in all types of vehicles. With gas prices still high, however, the report suggested that motorcycle riders may have decided "to use their fuel-efficient motorcycles rather than automobiles for commuting and other everday travel," thus increasing rider deaths.

The report recommended that states address a number of issues in order to reduce motorcycle deaths, especially encouraging an increase in helmet use. "The most effective strategy by far," asserted the report, "is to enact a universal helmet law in the [states] that lack them." Only 19 states now require riders to wear helmets, down from 26 in 1997.

The last state to enact a helmet requirement was Louisiana in 2004. In 2012, Michigan dropped its requirement and made helmets voluntary.

Michigan's new law went into effect last April. Preliminary totals from the Michigan Office of Highway Safety Planning projected 129 motorcyclist deaths in the state for 2012, an 18 percent increase over 2011.

The Michigan chapter of ABATE, a motorcyclist group opposed to mandatory helmet laws, said in a statement to NBC News that the fatalities "fall within the normal range of variation" and can't be attributed to the relaxed law. ABATE also referenced the warm weather and an increase in registration as possible factors. "Our primary concern about the accuracy of the data from (the state Office of Highway Safety Planning) is that two single points of data are being compared, when a multiyear comparison will give the clearest and most accurate depiction," said Vince Piacenti, statistician for ABATE Michigan.

Hedlund said that he had not analyzed the Michigan data, but said the variation was not small. "Numbers can vary, particularly in fairly small states," he said, "but Michigan's numbers went up substantially."

ABATE also noted that more than half of Michigan bikers who died in 2012 were "not endorsed to operate a motorcycle." GHSA's recommenddations for cutting motorcyclist deaths include reducing alcohol impairment, reducing speeding and ensuring that motorcyclists are licensed. According to GHSA, NHTSA data shows that in 2010, nearly a quarter of riders involved in fatal accidents did not have valid licenses.

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Vampire Weekend And Steve Buscemi Befuddle Tourists In Exclusive Clip

VW and Buscemi get the word out about the band's "American Express Unstaged" concert on April 28.
By James Montgomery

Source: http://www.mtv.com/news/articles/1706236/vampire-weekend-steve-buscemi-american-express-unstaged.jhtml

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'Dancing' dud Andy Dick struggles again

Craig Sjodin / Craig Sjodin / ABC

By Ree Hines, TODAY contributor

The ballroom battle continued to heat up on "Dancing With the Stars" Monday night, but there was more than one battle going on in the competition.

At the top of the leaderboard, the fight was for first-place bragging rights -- ?and that continued to be a neck-and-neck battle between "Dancing" queens Zendaya and Kellie Pickler (more on that later). But from the back of the pack, Andy Dick was fighting too -- fighting to stay in the competition.

Andy is far from the best dancer, but what the actor-comedian lacks in technique, he more than makes up for with sincerity and fun.

For his latest routine, he attempted a sexy samba with partner Sharna Burgess. What he delivered didn't exactly look like a samba, and it certainly wasn't sexy. But it was big on personality, and there wasn't anything halfhearted about it.

"Andy, if the others have climbed hills, you have climbed mountains," head judge Len Goodman said of his efforts.

But moving mountains doesn't show up on the scoreboard. Len and his fellow panelists gave Andy 6s all around.

Fair enough -- or at least it would have been, had the judges not given former "Bachelor" Sean Lowe three more points than that for his own seriously flawed samba.

Len told Sean he needed to set his sights higher than just beating Andy -- a low blow that earned boos from Andy's fans

"Is that the best you can do with the booing?!" Len asked, egging on the crowd.

If that slight made Andy's supporters unhappy, their moods didn't improve after Victor Ortiz took the floor. The boxer looked lost throughout his rumba routine and obviously missed a few steps along the way. Heck, he knew it was bad -- he was shaking his head when it was all over. Still, what turned out to be the worst dance of the night earned him the exact same score as Andy.

The other stars had a far better night. Actor Ingo Rademacher put on his best dance yet with a 24-point tango, and Aly Raisman beat him with her flowing 27-point foxtrot.

And as for the aforementioned "Dancing" queens, they both proved worthy of heir matching scores of 29 points. Zendaya's near-perfect cha-cha wowed the crowd, and Kellie's quickstep wowed Len (who handed out his first 10 of the season for it).

But everyone had one more chance to add to their scores before the night was over. In honor of the show's theme for the evening -- Stevie Wonder night -- the celebs split into teams for group routines.

Team Paso, made up of Zendaya, Ingo, Jacoby and Victor, moved to "Higher Ground," while Team Samba (Kellie, Sean, Aly and Andy) grooved to "Supersition." The judges favored the latter act, giving the samba set a score of 25 points versus 23 for the other team. And that made all the difference when it came to the various ballroom battles.

Suddenly the "Dancing" queens weren't neck-and-neck, as Kellie nabbed the lead for the night.

And Andy? He just barely climbed out of last place thanks to those extra points. Of course, only time will tell if he has enough support from fans to stick around on beyond Tuesday night.

Do you think Andy Dick should survive another week in the ballroom bash? Share your thoughts on our Facebook page.

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Source: http://theclicker.today.com/_news/2013/04/22/17868354-dancing-with-the-stars-dud-andy-dick-struggles-to-survive-another-week?lite

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PSA: Twitter is down for some, as is iCloud and the iTunes Store (update: both are back up!)

PSA Twitter is down for some, as is iCloud and the iTunes Store

Nope, it's not your picture of "the best duck confit I've ever had" that's causing that Twitter post to error out -- the service is down for "some users," according to a Twitter status page update. It's unknown what's causing the issue (again, probably not your photweet), but we're assured "engineers are currently working on this issue." We're experiencing some snags ourselves, usually resulting in tweets timing out before publishing. Hang tight!

But maybe don't try to while away your time on the iTunes Store or by backing up your phone to iCloud, as those services are also experiencing some downtime issues this morning. An Apple support page lists both as seeing "some users affected;" we'll just have to assume engineers are also hard at work on fixing that. As always, we'll let you know when things get better.

Update: Looks like Twitter is all back to normal, and the company says, "this issue has been resolved." Apple, on the other hand, is still having issues with Apple ID and Game Center login.

Update 2: Apple is now all back to normal as well, according to the company's support page. But do let us know if you're experiencing any issues!

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Source: Twitter, Apple

Source: http://www.engadget.com/2013/04/23/psa-twitter-icloud-itunes-issues/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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